William married Isabella Houghton about 1535 in , Lancashire, England. Isabella was born in 1515 in Hoghton, Lancashire, England. [Group Sheet] [Family Chart]

1. William Holden III was born on 26 Mar 1553 in Lindsey, Suffolk, England; was christened in Suffolk, England; died on 8 Oct 1619 in Lindsey, Suffolk, England; was buried on 8 Oct 1619 in Lindsey, Suffolk, England.
2. Gilbert Holden was born in 1535 in Haslingden, Lancashire, England, United Kingdom; died in 1571 in Haslingden, Lancashire, England.
3. Robert Greave Holden was born in 1540 in Holden in Haslingden, Lancashire, England, United Kingdom; was christened in 1575; died in 1637 will; was buried in 1637.
4. Agnes Holden was born in 1542 in Burnley, Lancashire, England.
5. George Holden was born in 1545 in Piccope Bank, Lancashire, England; died in 1626.
6. Adam Holden was born in 1547 in Lindsey, Suffolk, England.
7. Bridget Holden was born in 1548 in Suffolk, England.
8. Richard Holden was born about 1550 in Suffolk, England; died in 1625.
9. Adam Holden was born in 1555 in Lindsey, Suffolk, England; died in Lindsey, Suffolk, England.
10. Jone Holden was born in 1557 in Suffolk, England.