| Children |
| | 1. Ammi Ruhami Wise, b. Abt 1684, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America  d. 9 Jul 1749, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America (Age 65 years) |
| | 2. Rev. Jeremiah Wise, b. 2 Sep 1679, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America d. 21 Jan 1756, Berwick, York, Province of Maine, British Colonial America (Age 76 years) |
| | 3. Lucy Wise, b. 1681, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America d. 5 Mar 1727, Gloucester, Essex, Massachusetts Bay Colony, British Colonial America (Age 46 years) |
| | 4. John Wise, b. 1683, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America d. 31 Aug 1762, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America (Age 79 years) |
| | 5. Mary Wise, b. 12 May 1685, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America d. 23 Mar 1736, Essex, Essex, Massachusetts Bay Colony, British Colonial America (Age 50 years) |
| | 6. Dr. Joseph Wise, b. 16 Feb 1687, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America d. 23 Sep 1745, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America (Age 58 years) |
| | 7. Henry Wise, b. Abt 1688, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America d. 12 Nov 1775, Ipswich, Essex, Massachusetts Bay Colony, British Colonial America (Age 87 years) |
|
1652 - 1735 (82 years)
