Isaac married Mary Sisson in 1672 in Portsmouth, Newport, Rhode Island, British Colonial America. Mary was born in 1654 in Dartmouth, Bristol, Massachusetts Bay, British Colonial America; died in 1674 in Dartmouth, Bristol, Massachusetts Bay, British Colonial America. [Group Sheet] [Family Chart]

Isaac married Elizabeth Tallman on 3 Mar 1674 in Portsmouth, Newport, Colony of Rhode Island, British Colonial America. Elizabeth was born about 1654 in Portsmouth, Newport, Rhode Island, British Colonial America; died on 20 May 1701 in Portsmouth, Newport, Rhode Island, British Colonial America; was buried in May 1701 in Portsmouth, Newport, Rhode Island, British Colonial America. [Group Sheet] [Family Chart]

Isaac married Naomi Hunt on 11 Oct 1701 in Portsmouth, Newport, Rhode Island, United States. Naomi was born on 15 Sep 1658 in Portsmouth, Newport, Rhode Island, British Colonial America; was christened in Newport, Newport, Rhode Island; died on 13 Jan 1721 in Portsmouth, Newport, Rhode Island, British Colonial America. [Group Sheet] [Family Chart]